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While we are taking full responsibility for any remaining er
2019-12-02
While we are taking full responsibility for any remaining errors and shortcomings of the paper, we would like to thank Dr. Jong-Hyeon Jeong, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, for offering us insight and literature pointers useful in our quest to
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Second when considering the Poisson
2019-12-02
Second, when considering the Poisson point process, the high-density or large-radius limit of the percolation probability tends to 1 exponentially fast and is governed by the isolation probability. In the random environment, the picture is more subtle since the regime of a large radius is no longer
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Located on the fore tarsals of the front pair of
2019-12-02
Located on the fore-tarsals of the front pair of legs, the Haller’s organ is presumed central to tick chemosensation. Recent genomic, transcriptomic and proteomic investigations have identified several families of transmembrane proteins in the forelegs of ticks that are likely involved in olfactory
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As the primary model we selected LDL receptor
2019-12-02
As the primary model we selected LDL-receptor knockout mice because these resemble the human plasma lipoprotein profile more closely. Currently, genetic models with reduced milk cholesterol content, which mimic cholesterol-free formula feeding, are unavailable. Thus, instead of modifying milk choles
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On the one hand levels of up to nM P
2019-12-02
On the one hand, levels of up to 20 nM P4 have been reported for a cyprinid species, Labeo rohita, in summer (Suresh et al., 2008). Similarly, P4 concentrations in tilapia, Oreochromis mossambicus, were found to range up to 27 nM (Cornish, 1998). Nevertheless in sturgeon P4 levels of approximately 3
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To our knowledge immunohistochemical analysis for
2019-12-02
To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor Levodopa mg were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated serum pro
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AZD6482 ERR is present early in the developing
2019-12-02
ERRβ is present early in the developing placenta in a subset of AZD6482 in extra-embryonic ectoderm destined to make up the chorion.19, 20 ERRβ is likely essential for reproduction. ERRβ expression is essential for the maintenance of pluripotency and self-renewal potential in mouse embryonic stem ce
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The mechanisms by which Cav
2019-12-02
The mechanisms by which Cav-1 enhances embryonal tumor progression are currently unknown. Given the documented ability of Cav-1 to drive increased biogenesis of caveolae and accelerate the flow of nutrients (mostly glucose and fatty acids) across the membrane, as observed in particular in adipocytes
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Introduction Fish commonly employ pheromones to regulate a v
2019-12-02
Introduction Fish commonly employ pheromones to regulate a variety of functions including reproductive communication [1]. Reproductive pheromones induce both primer effects, such as changes in the endocrine or physiological state of conspecifics, and releaser effects such as rapid behavioral respon
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br Introduction The protein Epidermal
2019-12-02
Introduction The protein Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) play important role in non small-cell lung carcinoma (NSCLC) and vital therapeutic progress withinin the treatment of this ailment has revamped the past ten years through the exploitation of this insight (Mok et a
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One question relates to our finding that oxysterol GPR signa
2019-12-02
One question relates to our finding that oxysterol-GPR183 signaling is critical for CP and ILF formation in the colon but dispensable in the small intestine. GPR183 and its ligand were expressed in both the small and large intestines. Moreover, 7α,25-OHC was required for ILC3 migration to CPs not on
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In mice our EBI EGFP reporter showed that EBI
2019-12-02
In mice, our EBI2EGFP reporter showed that EBI2 is expressed consistently in naive T helper cells. Already single positive CD4+ thymocytes express EBI2 (not shown). In effector and regulatory T cells in naive mice, the percentage of EBI2 expression was lower (∼40%). Like others (Liu et al., 2011), w
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br Discussion Our data demonstrate that the bicyclam AMD str
2019-11-30
Discussion Our data demonstrate that the bicyclam AMD3100 strongly interacts with CXCR-4, whereas DS and AR177, two other compounds that also interfere with virus entry into the rna polymerase (and interfere with virus binding), do not. AMD3100 is a unique compound in that it interferes with the
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br Data deposition The structure factor amplitudes and coord
2019-11-30
Data deposition: The structure factor amplitudes and coordinates of mIL34 and the mIL-34:mCSF-1R complex have been deposited in the Protein Data Bank, www.pdb.org, with accession codes 4EXN and 4EXP. Note added in proof The authors would like to inform the readers of two recent articles that ar
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Preliminary studies evidenced the presence
2019-11-30
Preliminary studies evidenced the presence of CRFr in gamma-aminobutyric acid-ergic (GABAergic) neurons of the hippocampus (Yan et al., 1998). In fact, in this Mizoribine area, CRF inhibits glutamate release through CRF1r (Bagosi et al., 2015), leading to a decrease in the GABA concentration in the
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