• ITF2357 LQT can have numerous clinical

  2019-05-06

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

• br Conclusions br Disclosures br Funding Sources br Introduc

  2019-05-06

  

  Conclusions Disclosures Funding Sources Introduction Pulmonary vein isolation (PVI) has become an accepted treatment for atrial fibrillation (AF) [1]. The efficacy of PVI is sometimes insufficient, and atrial substrate modification of target specific AF signals indicating the substrate r

• YM 155 manufacturer A lo largo de todo el siglo abundan

  2019-05-06

  

  A lo largo de todo el siglo abundan las obras literarias incitadas por la búsqueda y promoción de la originalidad del continente; en el terreno lírico, la del argentino Juan María Gutiérrez (1809-1878) se erige como una de las más genuinas expresiones de esta tradición americanista. No por mero azar

• Perteneciente a la representaci n

  2019-05-06

  

  Perteneciente Nutlin-3 la representación que Hanumān realiza del , Acosta emplea un apto neologismo, el de “hu-mono” (171). Con este término se enfatiza hasta qué punto el narrador y el mono son reflejos el uno del otro. El salto físico del mono gramático inspira otros saltos en el lenguaje de Paz.

• Inhaled corticosteroids long acting agonists and

  2019-05-06

  

  Inhaled corticosteroids, long-acting β-agonists, and long-acting muscarinic agonists are all expensive drugs and many patients in China cannot afford them. An alternative pharmacological treatment for COPD, phosphodiesterase-4 inhibitor, is awaiting approval by the China State Food and Drug Adminis

• br We appreciate the response by Sharath Nagaraja and

  2019-05-06

  

  We appreciate the response by Sharath Nagaraja and Ritesh Menezes to our Comment, in which we had argued that patients with tuberculosis deserve a complete and patient-centric solution, irrespective of whether they seek care in the public or private health sector. Nagaraja and Menezes seem to have

• br Deseo y nostalgia el discurso

  2019-05-06

  

  Deseo y nostalgia: el discurso de lo real en la Historia verdadera Más allá de las afirmaciones de verdad y realidad en las que el texto incurre a cada paso; más allá del detalle (en sus usos narratológicos, retóricos y polémicos); más allá de cierta mimesis entendida como artificio y concebida t

• Independientemente del estado de nimo de los agentes

  2019-05-05

  

  Independientemente del estado de ánimo de los agentes del gobierno colonial, ante el fin de la ocupación militar, La Lucha presentaba el advenimiento de la República de Cuba como un hecho con claroscuros para diferentes sectores de la sociedad cubana; por un lado, se anhelaba la salida del gobierno

• In addition further study is required to evaluate

  2019-05-05

  

  In addition, further study is required to evaluate whether identified mutations influence post-translational modifications because they are important mechanism of transcription factors for regulating normal and leukemic hematopoiesis. Authors\' contributions Conflict of interest Acknowledgm

• In Fatima Mir and colleagues

  2019-05-05

  

  In , Fatima Mir and colleagues report results from the Simplified Antibiotic Therapy Trial (SATT) in Pakistan, in which three antibiotic regimens were compared for treatment of neonatal infections: procaine benzylpenicillin and gentamicin; amoxicillin and gentamicin; and procaine benzylpenicillin, g

• The patient underwent surgery on December A

  2019-05-05

  

  The patient underwent surgery on December 2, 2013. A 13 × 13 cm elastic lobulated yellowish tumor, arising from the upper jejunum with suspected local invasion into the transverse colon and mesentery, was detected intraoperatively. Thus, small bowel segmental resection and left hemicolectomy were pe

• The tumor microenvironment is enriched with EMVs that are de

  2019-05-05

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• Additionally the selection for subcutaneous ICD implant is

  2019-05-05

  

  Additionally, the selection for subcutaneous ICD implant is based on pre-implant electrographic body surface mapping. The sensing algorithm for this system depends on the surface elecrtrocardiogram (ECG) morphology, specifically the R-and T-wave amplitudes, R/T and R/P ratios, QRS duration and QT in

• Ideally assessment of obstetric interventions and outcomes s

  2019-05-05

  

  Ideally, assessment of obstetric interventions and outcomes should be based on high-quality, recent data from the entire population or a representative sample. A key feature of the Robson classification is that it uses information that is available at the onset of labour or delivery, is routinely co

• Although the CHADS score is

  2019-05-04

  

  Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so

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